2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide
TL;DR: 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide (CAS 1378306-70-7) is a chemical compound with molecular formula C10H11ClF3NO2S and molecular weight 301.0151 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-chloro-N-propan-2-yl-5-(trifluoromethyl)benzenesulfonamide
Also Known As: 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide, 2-chloro-N-propan-2-yl-5-(trifluoromethyl)benzenesulfonamide, 2-chloro-N-isopropyl-5-(trifluoromethyl)benzenesulfonamide, G57518
Technical Specifications
| Molecular Formula | C10H11ClF3NO2S |
| Molecular Weight | 301.0151 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 54.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 301.0151 Da |
| Heavy Atoms | 18 |
| Complexity | 378.0 |
| SMILES | CC(C)NS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)Cl |
| InChIKey | GBKBIDBAMJWRTE-UHFFFAOYSA-N |
Chemical Property Profile of 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide
Property Insights of 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide
The XLogP value of 3.2 indicates that 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.6 Ų, 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide?
The CAS number of 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide is 1378306-70-7.
What is the molecular formula of 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide?
The molecular formula of 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide is C10H11ClF3NO2S.
What is the molecular weight of 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide?
The molecular weight of 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide is 301.0151 g/mol.
Where can I buy 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide?
You can request a quote for 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide?
Yes, CoreyChem provides custom synthesis services for 2-chloro-N-(propan-2-yl)-5-(trifluoromethyl)benzene-1-sulfonamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.