N-(3-fluoropropyl)paroxetine
TL;DR: N-(3-fluoropropyl)paroxetine (CAS 138135-14-5) is a chemical compound with molecular formula C22H25F2NO3 and molecular weight 389.18024 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)-1-(3-fluoropropyl)piperidine
Also Known As: 3-Nfpp, N-(3-Fluoropropyl)paroxetine, N-(3-(18F)Fluoropropyl)paroxetine, (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)-1-(3-fluoropropyl)piperidine, (3S,4R)-3-((BENZO[D][1,3]DIOXOL-5-YLOXY)METHYL)-4-(4-FLUOROPHENYL)-1-(3-FLUOROPROPYL)PIPERIDINE
Technical Specifications
| Molecular Formula | C22H25F2NO3 |
| Molecular Weight | 389.18024 g/mol |
| XLogP | 4.7 |
| Topological Polar Surface Area (TPSA) | 30.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 389.18024 Da |
| Heavy Atoms | 28 |
| Complexity | 475.0 |
| SMILES | C1CN(C[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4)CCCF |
| InChIKey | FUCBTTRMHIHFNU-PXNSSMCTSA-N |
Chemical Property Profile of N-(3-fluoropropyl)paroxetine
Property Insights of N-(3-fluoropropyl)paroxetine
The XLogP value of 4.7 indicates that N-(3-fluoropropyl)paroxetine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 30.9 Ų, N-(3-fluoropropyl)paroxetine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(3-fluoropropyl)paroxetine has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-(3-fluoropropyl)paroxetine?
The CAS number of N-(3-fluoropropyl)paroxetine is 138135-14-5.
What is the molecular formula of N-(3-fluoropropyl)paroxetine?
The molecular formula of N-(3-fluoropropyl)paroxetine is C22H25F2NO3.
What is the molecular weight of N-(3-fluoropropyl)paroxetine?
The molecular weight of N-(3-fluoropropyl)paroxetine is 389.18024 g/mol.
Where can I buy N-(3-fluoropropyl)paroxetine?
You can request a quote for N-(3-fluoropropyl)paroxetine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-(3-fluoropropyl)paroxetine?
Yes, CoreyChem provides custom synthesis services for N-(3-fluoropropyl)paroxetine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.