TL;DR: (3Z)-5-methyl-3-[2-(quinolin-2-yl)hydrazinylidene]-1,3-dihydro-2H-indol-2-one (CAS 138344-66-8) is a chemical compound with molecular formula C18H14N4O and molecular weight 302.11676 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-methyl-3-(quinolin-2-yldiazenyl)-1H-indol-2-ol
Also Known As: 5-methyl-3-(2-quinolin-2-ylhydrazinyl)indol-2-one, 5-methyl-3-(2-(quinolin-2-yl)hydrazinyl)-2H-indol-2-one, (Z)-5-methyl-3-(2-(quinolin-2-yl)hydrazono)indolin-2-one, (3Z)-5-methyl-3-[(2E)-quinolin-2(1H)-ylidenehydrazinylidene]-1,3-dihydro-2H-indol-2-one, (3Z)-5-methyl-3-[2-(quinolin-2-yl)hydrazinylidene]-1,3-dihydro-2H-indol-2-one
| Molecular Formula | C18H14N4O |
| Molecular Weight | 302.11676 g/mol |
| XLogP | 4.8 |
| Topological Polar Surface Area (TPSA) | 73.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 302.11676 Da |
| Heavy Atoms | 23 |
| Complexity | 443.0 |
| SMILES | CC1=CC2=C(C=C1)NC(=C2N=NC3=NC4=CC=CC=C4C=C3)O |
| InChIKey | TUJUYNHRNIXFBD-UHFFFAOYSA-N |
The XLogP value of 4.8 indicates that (3Z)-5-methyl-3-[2-(quinolin-2-yl)hydrazinylidene]-1,3-dihydro-2H-indol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 73.6 Ų falls within the moderate polarity range, balancing permeability and solubility for (3Z)-5-methyl-3-[2-(quinolin-2-yl)hydrazinylidene]-1,3-dihydro-2H-indol-2-one. Following Lipinski's Rule of Five, (3Z)-5-methyl-3-[2-(quinolin-2-yl)hydrazinylidene]-1,3-dihydro-2H-indol-2-one has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of (3Z)-5-methyl-3-[2-(quinolin-2-yl)hydrazinylidene]-1,3-dihydro-2H-indol-2-one is 138344-66-8.
The molecular formula of (3Z)-5-methyl-3-[2-(quinolin-2-yl)hydrazinylidene]-1,3-dihydro-2H-indol-2-one is C18H14N4O.
The molecular weight of (3Z)-5-methyl-3-[2-(quinolin-2-yl)hydrazinylidene]-1,3-dihydro-2H-indol-2-one is 302.11676 g/mol.
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