SQ-31765 free base
TL;DR: SQ-31765 free base (CAS 138383-07-0) is a chemical compound with molecular formula C24H27F3N2O4 and molecular weight 464.1923 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[(3R,4S)-1-[2-(dimethylamino)ethyl]-4-(4-methoxyphenyl)-2-oxo-6-(trifluoromethyl)-4,5-dihydro-3H-1-benzazepin-3-yl] acetate
Also Known As: SQ-31765 free base, 2H-1-Benzazepin-2-one, 3-(acetyloxy)-1-(2-(dimethylamino)ethyl)-1,3,4,5-tetrahydro-4-(4-methoxyphenyl)-6-(trifluoromethyl)-, (3R,4S)-, [(3R,4S)-1-[2-(dimethylamino)ethyl]-4-(4-methoxyphenyl)-2-oxo-6-(trifluoromethyl)-4,5-dihydro-3H-1-benzazepin-3-yl] acetate, (3R,4S)-1-[2-(dimethylamino)ethyl]-4-(4-methoxyphenyl)-2-oxo-6-(trifluoromethyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl acetate, (3R)-1-(2-Dimethylaminoethyl)-4,5-dihydro-3alpha-acetyloxy-4alpha-(4-methoxyphenyl)-6-trifluoromethyl-1H-1-benzazepin-2(3H)-one
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C24H27F3N2O4 |
| Molecular Weight | 464.1923 g/mol |
| XLogP | 3.9 |
| Topological Polar Surface Area (TPSA) | 59.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 7 |
| Exact Mass | 464.1923 Da |
| Heavy Atoms | 33 |
| Complexity | 679.0 |
| SMILES | CC(=O)O[C@@H]1[C@@H](CC2=C(C=CC=C2N(C1=O)CCN(C)C)C(F)(F)F)C3=CC=C(C=C3)OC |
| InChIKey | GZJHZWDNNABIOE-PGRDOPGGSA-N |
Chemical Property Profile of SQ-31765 free base
Property Insights of SQ-31765 free base
The XLogP value of 3.9 indicates that SQ-31765 free base is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.1 Ų, SQ-31765 free base exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, SQ-31765 free base has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of SQ-31765 free base?
The CAS number of SQ-31765 free base is 138383-07-0.
What is the molecular formula of SQ-31765 free base?
The molecular formula of SQ-31765 free base is C24H27F3N2O4.
What is the molecular weight of SQ-31765 free base?
The molecular weight of SQ-31765 free base is 464.1923 g/mol.
Where can I buy SQ-31765 free base?
You can request a quote for SQ-31765 free base directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for SQ-31765 free base?
Yes, CoreyChem provides custom synthesis services for SQ-31765 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.