5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole
TL;DR: 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole (CAS 138900-27-3) is a chemical compound with molecular formula C19H18ClFN2 and molecular weight 328.11426 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-chloro-1-(4-fluorophenyl)-3-piperidin-4-ylindole
Also Known As: 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole, 5-Chloro-1-(4-fluoro-phenyl)-3-piperidin-4-yl-1H-indole, 6717AA, 5-Chloro-1-(4-fluorophenyl)-3-piperidin-4-ylindole, Lu-25-073
Technical Specifications
| Molecular Formula | C19H18ClFN2 |
| Molecular Weight | 328.11426 g/mol |
| XLogP | 4.5 |
| Topological Polar Surface Area (TPSA) | 17.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 328.11426 Da |
| Heavy Atoms | 23 |
| Complexity | 393.0 |
| SMILES | C1CNCCC1C2=CN(C3=C2C=C(C=C3)Cl)C4=CC=C(C=C4)F |
| InChIKey | YCXCLZSLZGBCTA-UHFFFAOYSA-N |
Chemical Property Profile of 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole
Property Insights of 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole
The XLogP value of 4.5 indicates that 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 17.0 Ų, 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole?
The CAS number of 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole is 138900-27-3.
What is the molecular formula of 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole?
The molecular formula of 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole is C19H18ClFN2.
What is the molecular weight of 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole?
The molecular weight of 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole is 328.11426 g/mol.
Where can I buy 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole?
You can request a quote for 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole?
Yes, CoreyChem provides custom synthesis services for 5-Chloro-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.