N-Ethyl-N'-(5-nitro-2-thiazolyl)urea
TL;DR: N-Ethyl-N'-(5-nitro-2-thiazolyl)urea (CAS 139-94-6) is a chemical compound with molecular formula C6H8N4O3S and molecular weight 216.03171 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-ethyl-3-(5-nitro-1,3-thiazol-2-yl)urea
Also Known As: Nithiazide, Hepzide, Nithiazid, Hepzide 30, 1-Ethyl-3-(5-nitrothiazol-2-yl)urea
Application Areas
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H8N4O3S |
| Molecular Weight | 216.03171 g/mol |
| XLogP | 1.5 |
| Topological Polar Surface Area (TPSA) | 128.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 216.03171 Da |
| Heavy Atoms | 14 |
| Complexity | 232.0 |
| Melting Point | 442 °F (decomposes) (NTP, 1992) |
| Solubility | less than 1 mg/mL at 73 °F (NTP, 1992) |
| SMILES | CCNC(=O)NC1=NC=C(S1)[N+](=O)[O-] |
| InChIKey | FQSUTLQHSDLLAN-UHFFFAOYSA-N |
Product Description
Applications: N-Ethyl-N'-(5-nitro-2-thiazolyl)urea is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
N-Ethyl-N'-(5-nitro-2-thiazolyl)urea (CAS 139-94-6) is a pharmaceutical intermediate with the molecular formula C6H8N4O3S and a molecular weight of 216.03 g/mol. Key physical properties include a solubility: less than 1 mg/mL at 73 °F (NTP, 1992). Synonyms include Nithiazide and Hepzide.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of N-Ethyl-N'-(5-nitro-2-thiazolyl)urea
Property Insights of N-Ethyl-N'-(5-nitro-2-thiazolyl)urea
The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-Ethyl-N'-(5-nitro-2-thiazolyl)urea. The TPSA of 128.0 Ų falls within the moderate polarity range, balancing permeability and solubility for N-Ethyl-N'-(5-nitro-2-thiazolyl)urea. Following Lipinski's Rule of Five, N-Ethyl-N'-(5-nitro-2-thiazolyl)urea has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-Ethyl-N'-(5-nitro-2-thiazolyl)urea?
The CAS number of N-Ethyl-N'-(5-nitro-2-thiazolyl)urea is 139-94-6.
What is the molecular formula of N-Ethyl-N'-(5-nitro-2-thiazolyl)urea?
The molecular formula of N-Ethyl-N'-(5-nitro-2-thiazolyl)urea is C6H8N4O3S.
What is the molecular weight of N-Ethyl-N'-(5-nitro-2-thiazolyl)urea?
The molecular weight of N-Ethyl-N'-(5-nitro-2-thiazolyl)urea is 216.03171 g/mol.
What are the applications of N-Ethyl-N'-(5-nitro-2-thiazolyl)urea?
N-Ethyl-N'-(5-nitro-2-thiazolyl)urea is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both...
Where can I buy N-Ethyl-N'-(5-nitro-2-thiazolyl)urea?
You can request a quote for N-Ethyl-N'-(5-nitro-2-thiazolyl)urea directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-Ethyl-N'-(5-nitro-2-thiazolyl)urea?
Yes, CoreyChem provides custom synthesis services for N-Ethyl-N'-(5-nitro-2-thiazolyl)urea and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.