Bosutinib
TL;DR: Bosutinib (CAS 1391063-17-4) is a chemical compound with molecular formula C26H29Cl2N5O3 and molecular weight 529.16473 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-(2,4-dichloro-5-methoxyanilino)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile
Also Known As: Bosutinib, Bosutinib (SKI-606), BOSULIF, bosutinibum, SKI 606
Technical Specifications
| Molecular Formula | C26H29Cl2N5O3 |
| Molecular Weight | 529.16473 g/mol |
| XLogP | 5.4 |
| Topological Polar Surface Area (TPSA) | 82.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 9 |
| Exact Mass | 529.16473 Da |
| Heavy Atoms | 36 |
| Complexity | 734.0 |
| SMILES | CN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)OC)C#N)OC |
| InChIKey | UBPYILGKFZZVDX-UHFFFAOYSA-N |
Chemical Property Profile of Bosutinib
Property Insights of Bosutinib
The XLogP value of 5.4 indicates that Bosutinib is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 82.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Bosutinib. Following Lipinski's Rule of Five, Bosutinib has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Bosutinib?
The CAS number of Bosutinib is 1391063-17-4.
What is the molecular formula of Bosutinib?
The molecular formula of Bosutinib is C26H29Cl2N5O3.
What is the molecular weight of Bosutinib?
The molecular weight of Bosutinib is 529.16473 g/mol.
Where can I buy Bosutinib?
You can request a quote for Bosutinib directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Bosutinib?
Yes, CoreyChem provides custom synthesis services for Bosutinib and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.