(Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one
TL;DR: (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one (CAS 139276-19-0) is a chemical compound with molecular formula C16H11FO3 and molecular weight 270.0692 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2Z)-2-[(4-fluorophenyl)methylidene]-6-methoxy-1-benzofuran-3-one
Also Known As: (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one, (2Z)-2-[(4-fluorophenyl)methylidene]-6-methoxy-2,3-dihydro-1-benzofuran-3-one, (2Z)-2-[(4-fluorophenyl)methylidene]-6-methoxy-1-benzofuran-3-one, (2Z)-2-(4-fluorobenzylidene)-6-methoxy-1-benzofuran-3(2H)-one, F3139-1911
Technical Specifications
| Molecular Formula | C16H11FO3 |
| Molecular Weight | 270.0692 g/mol |
| XLogP | 3.7 |
| Topological Polar Surface Area (TPSA) | 35.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 270.0692 Da |
| Heavy Atoms | 20 |
| Complexity | 399.0 |
| SMILES | COC1=CC2=C(C=C1)C(=O)/C(=C/C3=CC=C(C=C3)F)/O2 |
| InChIKey | UDOJHQCINYEDFT-NVNXTCNLSA-N |
Chemical Property Profile of (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one
Property Insights of (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one
The XLogP value of 3.7 indicates that (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.5 Ų, (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one?
The CAS number of (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one is 139276-19-0.
What is the molecular formula of (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one?
The molecular formula of (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one is C16H11FO3.
What is the molecular weight of (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one?
The molecular weight of (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one is 270.0692 g/mol.
Where can I buy (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one?
You can request a quote for (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one?
Yes, CoreyChem provides custom synthesis services for (Z)-2-(4-fluorobenzylidene)-6-methoxybenzofuran-3(2H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.