Rifaximin Impurity B
TL;DR: Rifaximin Impurity B (CAS 13929-35-6) is a chemical compound with molecular formula C39H49NO14 and molecular weight 755.3153 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[(13-acetyloxy-2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-27-yl)oxy]acetic acid
Also Known As: RIFAMYCIN B, Rifaximin Impurity B, Rifamycin B; Rifaximin EP Impurity B; Rifamycin EP Impurity A
Technical Specifications
| Molecular Formula | C39H49NO14 |
| Molecular Weight | 755.3153 g/mol |
| XLogP | 4.8 |
| Topological Polar Surface Area (TPSA) | 228.0 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 6 |
| Exact Mass | 755.3153 Da |
| Heavy Atoms | 54 |
| Complexity | 1460.0 |
| SMILES | CC1C=CC=C(C(=O)NC2=CC(=C3C(=C2O)C(=C(C4=C3C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)OCC(=O)O)C |
| InChIKey | SQTCRTQCPJICLD-UHFFFAOYSA-N |
Chemical Property Profile of Rifaximin Impurity B
Property Insights of Rifaximin Impurity B
The XLogP value of 4.8 indicates that Rifaximin Impurity B is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 228.0 Ų indicates high polarity, suggesting Rifaximin Impurity B may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Rifaximin Impurity B has 6 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Rifaximin Impurity B?
The CAS number of Rifaximin Impurity B is 13929-35-6.
What is the molecular formula of Rifaximin Impurity B?
The molecular formula of Rifaximin Impurity B is C39H49NO14.
What is the molecular weight of Rifaximin Impurity B?
The molecular weight of Rifaximin Impurity B is 755.3153 g/mol.
Where can I buy Rifaximin Impurity B?
You can request a quote for Rifaximin Impurity B directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Rifaximin Impurity B?
Yes, CoreyChem provides custom synthesis services for Rifaximin Impurity B and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.