Nithiamide
TL;DR: Nithiamide (CAS 140-40-9) is a chemical compound with molecular formula C5H5N3O3S and molecular weight 187.00516 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(5-nitro-1,3-thiazol-2-yl)acetamide
Also Known As: Nithiamide, 2-Acetamido-5-nitrothiazole, Aminitrozole, Acinitrazole, Aminitrozol
Application Areas
Top 5 of 8 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C5H5N3O3S |
| Molecular Weight | 187.00516 g/mol |
| XLogP | 1.3 |
| Topological Polar Surface Area (TPSA) | 116.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 187.00516 Da |
| Heavy Atoms | 12 |
| Complexity | 205.0 |
| SMILES | CC(=O)NC1=NC=C(S1)[N+](=O)[O-] |
| InChIKey | UJRRDDHEMZLWFI-UHFFFAOYSA-N |
Product Description
Applications: Nithiamide is used in pharmaceutical synthesis routes and API production, as well as peptide synthesis and amino acid derivative chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Nithiamide is a pharmaceutical intermediate identified by CAS number 140-40-9 and the molecular formula C5H5N3O3S and a molecular weight of 187.01 g/mol. Synonyms include Nithiamide and 2-Acetamido-5-nitrothiazole.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nithiamide
Property Insights of Nithiamide
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nithiamide. The TPSA of 116.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Nithiamide. Following Lipinski's Rule of Five, Nithiamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nithiamide?
The CAS number of Nithiamide is 140-40-9.
What is the molecular formula of Nithiamide?
The molecular formula of Nithiamide is C5H5N3O3S.
What is the molecular weight of Nithiamide?
The molecular weight of Nithiamide is 187.00516 g/mol.
What are the applications of Nithiamide?
Nithiamide is used in pharmaceutical synthesis routes and API production, as well as peptide synthesis and amino acid derivative chemistry. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to...
Where can I buy Nithiamide?
You can request a quote for Nithiamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nithiamide?
Yes, CoreyChem provides custom synthesis services for Nithiamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.