Amoxapine
TL;DR: Amoxapine (CAS 14028-44-5) is a chemical compound with molecular formula C17H16ClN3O and molecular weight 313.09818 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine
Also Known As: amoxapine, Asendin, Demolox, Amoxan, Moxadil
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H16ClN3O |
| Molecular Weight | 313.09818 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 36.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 313.09818 Da |
| Heavy Atoms | 22 |
| Complexity | 424.0 |
| Melting Point | 175-176 |
| Solubility | 1.71e-01 g/L |
| SMILES | C1CN(CCN1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl |
| InChIKey | QWGDMFLQWFTERH-UHFFFAOYSA-N |
Product Description
Applications: Amoxapine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Amoxapine (CAS 14028-44-5) has the molecular formula C17H16ClN3O and a molecular weight of 313.1 g/mol. Reported properties include a solubility: 1.71e-01 g/L. Synonyms include amoxapine and Asendin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Amoxapine
Property Insights of Amoxapine
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Amoxapine. With a topological polar surface area (TPSA) of 36.9 Ų, Amoxapine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Amoxapine has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Amoxapine?
The CAS number of Amoxapine is 14028-44-5.
What is the molecular formula of Amoxapine?
The molecular formula of Amoxapine is C17H16ClN3O.
What is the molecular weight of Amoxapine?
The molecular weight of Amoxapine is 313.09818 g/mol.
What are the applications of Amoxapine?
Amoxapine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Amoxapine?
You can request a quote for Amoxapine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Amoxapine?
Yes, CoreyChem provides custom synthesis services for Amoxapine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.