2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide
TL;DR: 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide (CAS 140651-14-5) is a chemical compound with molecular formula C8H5Cl2F2NO and molecular weight 238.97162 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide
Also Known As: 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide, N1-(4-chlorophenyl)-2-chloro-2,2-difluoroacetamide, J2.233.803J, N-(4-Chlorophenyl)-2,2-difluoro-2-chloroacetamide
Technical Specifications
| Molecular Formula | C8H5Cl2F2NO |
| Molecular Weight | 238.97162 g/mol |
| XLogP | 3.5 |
| Topological Polar Surface Area (TPSA) | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 238.97162 Da |
| Heavy Atoms | 14 |
| Complexity | 217.0 |
| SMILES | C1=CC(=CC=C1NC(=O)C(F)(F)Cl)Cl |
| InChIKey | ZTJWLHPPHIMQNM-UHFFFAOYSA-N |
Chemical Property Profile of 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide
Property Insights of 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide
The XLogP value of 3.5 indicates that 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide?
The CAS number of 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide is 140651-14-5.
What is the molecular formula of 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide?
The molecular formula of 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide is C8H5Cl2F2NO.
What is the molecular weight of 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide?
The molecular weight of 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide is 238.97162 g/mol.
Where can I buy 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide?
You can request a quote for 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide?
Yes, CoreyChem provides custom synthesis services for 2-chloro-N-(4-chlorophenyl)-2,2-difluoroacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.