Awl 60
TL;DR: Awl 60 (CAS 140716-14-9) is a chemical compound with molecular formula C57H65N9O8S and molecular weight 1035.4677 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
Also Known As: Awl 60, Tyr-pro-D-phe-phe-D-phe-D-trp-metnh2, Tyrosyl-prolyl-phenylalanyl-phenylalanyl-phenylalanyl-tryptophyl-methioninamide, (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide, L-Methioninamide, L-tyrosyl-L-prolyl-D-phenylalanyl-L-phenylalanyl-D-phenylalanyl-D-tryptophyl-
Technical Specifications
| Molecular Formula | C57H65N9O8S |
| Molecular Weight | 1035.4677 g/mol |
| XLogP | 5.4 |
| Topological Polar Surface Area (TPSA) | 296.0 Ų |
| Hydrogen Bond Donors | 9 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 25 |
| Exact Mass | 1035.4677 Da |
| Heavy Atoms | 75 |
| Complexity | 1870.0 |
| SMILES | CSCC[C@@H](C(=O)N)NC(=O)[C@@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@@H](CC3=CC=CC=C3)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@@H](CC5=CC=CC=C5)NC(=O)[C@@H]6CCCN6C(=O)[C@H](CC7=CC=C(C=C7)O)N |
| InChIKey | VOMQYBALZJIZLK-URSBCDAASA-N |
Chemical Property Profile of Awl 60
Property Insights of Awl 60
The XLogP value of 5.4 indicates that Awl 60 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 296.0 Ų indicates high polarity, suggesting Awl 60 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Awl 60 has 9 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Awl 60?
The CAS number of Awl 60 is 140716-14-9.
What is the molecular formula of Awl 60?
The molecular formula of Awl 60 is C57H65N9O8S.
What is the molecular weight of Awl 60?
The molecular weight of Awl 60 is 1035.4677 g/mol.
Where can I buy Awl 60?
You can request a quote for Awl 60 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Awl 60?
Yes, CoreyChem provides custom synthesis services for Awl 60 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.