Dodecamethylpentasiloxane
TL;DR: Dodecamethylpentasiloxane (CAS 141-63-9) is a chemical compound with molecular formula C12H36O4Si5 and molecular weight 384.146 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
bis[[dimethyl(trimethylsilyloxy)silyl]oxy]-dimethylsilane
Also Known As: DODECAMETHYLPENTASILOXANE, Pentasiloxane, dodecamethyl-, Silicone liquid, penta(dimethylsiloxane), 1,1,1,3,3,5,5,7,7,9,9,9-Dodecamethylpentasiloxane
Application Areas
Top 5 of 16 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H36O4Si5 |
| Molecular Weight | 384.146 g/mol |
| XLogP | 4.83 |
| Topological Polar Surface Area (TPSA) | 36.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 8 |
| Exact Mass | 384.146 Da |
| Heavy Atoms | 21 |
| Complexity | 313.0 |
| Melting Point | -80 °C |
| Boiling Point | 230 °C |
| Density | 0.8755 g/cu cm at 20 °C |
| Vapor Pressure | 4.50X10-2 mm Hg at 25 °C (extrapolated) |
| Refractive Index | Index of refraction: 1.3925 at 20 °C/D |
| Solubility | In water, 7.04X10-5 mg/L at 25 °C |
| SMILES | C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C |
| InChIKey | FBZANXDWQAVSTQ-UHFFFAOYSA-N |
Product Description
Applications: Dodecamethylpentasiloxane is used in pharmaceutical synthesis routes and API production, as well as polymer chemistry and functional materials synthesis. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Dodecamethylpentasiloxane (CAS 141-63-9) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Dodecamethylpentasiloxane is a pharmaceutical intermediate identified by CAS number 141-63-9 and the molecular formula C12H36O4Si5 and a molecular weight of 384.15 g/mol. Physically, the compound has a density of 0.8755 g/cu cm at 20 °C g/cm³, a solubility: In water, 7.04X10-5 mg/L at 25 °C. It is also known as DODECAMETHYLPENTASILOXANE and Pentasiloxane, dodecamethyl-.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Dodecamethylpentasiloxane
Property Insights of Dodecamethylpentasiloxane
The XLogP value of 4.83 indicates that Dodecamethylpentasiloxane is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 36.9 Ų, Dodecamethylpentasiloxane exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dodecamethylpentasiloxane has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Dodecamethylpentasiloxane?
The CAS number of Dodecamethylpentasiloxane is 141-63-9.
What is the molecular formula of Dodecamethylpentasiloxane?
The molecular formula of Dodecamethylpentasiloxane is C12H36O4Si5.
What is the molecular weight of Dodecamethylpentasiloxane?
The molecular weight of Dodecamethylpentasiloxane is 384.146 g/mol.
What are the applications of Dodecamethylpentasiloxane?
Dodecamethylpentasiloxane is used in pharmaceutical synthesis routes and API production, as well as polymer chemistry and functional materials synthesis. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Dodecamethylpentasiloxane (CAS 141-63-9) with...
Where can I buy Dodecamethylpentasiloxane?
You can request a quote for Dodecamethylpentasiloxane directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Dodecamethylpentasiloxane?
Yes, CoreyChem provides custom synthesis services for Dodecamethylpentasiloxane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.