Bcl-2 Inhibitor III
TL;DR: Bcl-2 Inhibitor III (CAS 141266-44-6) is a chemical compound with molecular formula C15H9ClN4O6 and molecular weight 376.02106 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-(7-chloro-2,4-dioxo-1,5-dihydrochromeno[2,3-d]pyrimidin-5-yl)-1,3-diazinane-2,4,6-trione
Also Known As: Bcl-2 Inhibitor III, EM20-25, Bcl-2 Inhibitor III, EM20-25, Bcl-2 inhibitor iii,em20-25, 5-(6-Chloro-2,4-dioxo-1,3,4,10-tetrahydro-2H-9-oxa-1,3-diaza-anthracen-10-yl)-pyrimidine-2,4,6-trione
Technical Specifications
| Molecular Formula | C15H9ClN4O6 |
| Molecular Weight | 376.02106 g/mol |
| XLogP | -0.2 |
| Topological Polar Surface Area (TPSA) | 143.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 376.02106 Da |
| Heavy Atoms | 26 |
| Complexity | 760.0 |
| SMILES | C1=CC2=C(C=C1Cl)C(C3=C(O2)NC(=O)NC3=O)C4C(=O)NC(=O)NC4=O |
| InChIKey | GGEVZGGAQHNWQN-UHFFFAOYSA-N |
Chemical Property Profile of Bcl-2 Inhibitor III
Property Insights of Bcl-2 Inhibitor III
The XLogP value of -0.2 indicates that Bcl-2 Inhibitor III is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 143.0 Ų indicates high polarity, suggesting Bcl-2 Inhibitor III may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Bcl-2 Inhibitor III has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Bcl-2 Inhibitor III?
The CAS number of Bcl-2 Inhibitor III is 141266-44-6.
What is the molecular formula of Bcl-2 Inhibitor III?
The molecular formula of Bcl-2 Inhibitor III is C15H9ClN4O6.
What is the molecular weight of Bcl-2 Inhibitor III?
The molecular weight of Bcl-2 Inhibitor III is 376.02106 g/mol.
Where can I buy Bcl-2 Inhibitor III?
You can request a quote for Bcl-2 Inhibitor III directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Bcl-2 Inhibitor III?
Yes, CoreyChem provides custom synthesis services for Bcl-2 Inhibitor III and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.