lamivudine
TL;DR: lamivudine (CAS 141434-39-1) is a chemical compound with molecular formula C8H11N3O3S and molecular weight 229.05211 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
Also Known As: lamivudine, Epivir, ent-Lamivudine, Epivir-HBV, CIS-LAMIVUDINE
Application Areas
Top 5 of 7 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H11N3O3S |
| Molecular Weight | 229.05211 g/mol |
| XLogP | -0.9 |
| Topological Polar Surface Area (TPSA) | 113.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 229.05211 Da |
| Heavy Atoms | 15 |
| Complexity | 331.0 |
| SMILES | C1C(OC(S1)CO)N2C=CC(=NC2=O)N |
| InChIKey | JTEGQNOMFQHVDC-UHFFFAOYSA-N |
Chemical Property Profile of lamivudine
Property Insights of lamivudine
The XLogP value of -0.9 indicates that lamivudine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 113.0 Ų falls within the moderate polarity range, balancing permeability and solubility for lamivudine. Following Lipinski's Rule of Five, lamivudine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of lamivudine?
The CAS number of lamivudine is 141434-39-1.
What is the molecular formula of lamivudine?
The molecular formula of lamivudine is C8H11N3O3S.
What is the molecular weight of lamivudine?
The molecular weight of lamivudine is 229.05211 g/mol.
Where can I buy lamivudine?
You can request a quote for lamivudine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for lamivudine?
Yes, CoreyChem provides custom synthesis services for lamivudine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.