5'-Silyl-2'dT TSAO deriv.
TL;DR: 5'-Silyl-2'dT TSAO deriv. (CAS 141684-49-3) is a chemical compound with molecular formula C18H29N3O7SSi and molecular weight 459.14954 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(6R,8R)-4-amino-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione
Also Known As: 5'-Silyl-2'dT TSAO deriv., (1-(5'-O-(tert-Butyldimethylsilyl)-2'-deoxy-beta-D-erythropentofuranosyl)thymine)-3'-spiro-5-(4-amino-1,2-oxathiole-2,2-dioxide), 1-[(2R,4R)-6-amino-4-[[tert-butyl(dimethyl)silyl]oxymethyl]-8,8-dioxo-3,9-dioxa-8, (6R,8R)-4-Amino-6-({[tert-butyldi(methyl)silyl]oxy}methyl)-8-(4-hydroxy-5-methyl-2-oxopyrimidin-1(2H)-yl)-1,7-dioxa-2lambda~6~-thiaspiro[4.4]non-3-ene-2,2-dione, [1-[5'-O-(tert-Butyldimethylsilyl)-2'-deoxy-.beta.-D-erythropentofuranosyl]thymine]-3'-spiro-5-[4-amino-1,2-oxathiole-2,2-dioxide]
Technical Specifications
| Molecular Formula | C18H29N3O7SSi |
| Molecular Weight | 459.14954 g/mol |
| XLogP | 1.05322 |
| Topological Polar Surface Area (TPSA) | 146.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 459.14954 Da |
| Heavy Atoms | 30 |
| Complexity | 932.0 |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2CC3([C@H](O2)CO[Si](C)(C)C(C)(C)C)C(=CS(=O)(=O)O3)N |
| InChIKey | CRPDUJBVAQMMLM-LPOUJYBBSA-N |
Chemical Property Profile of 5'-Silyl-2'dT TSAO deriv.
Property Insights of 5'-Silyl-2'dT TSAO deriv.
The XLogP value of 1.05322 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5'-Silyl-2'dT TSAO deriv.. The TPSA of 146.0 Ų indicates high polarity, suggesting 5'-Silyl-2'dT TSAO deriv. may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 5'-Silyl-2'dT TSAO deriv. has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5'-Silyl-2'dT TSAO deriv.?
The CAS number of 5'-Silyl-2'dT TSAO deriv. is 141684-49-3.
What is the molecular formula of 5'-Silyl-2'dT TSAO deriv.?
The molecular formula of 5'-Silyl-2'dT TSAO deriv. is C18H29N3O7SSi.
What is the molecular weight of 5'-Silyl-2'dT TSAO deriv.?
The molecular weight of 5'-Silyl-2'dT TSAO deriv. is 459.14954 g/mol.
Where can I buy 5'-Silyl-2'dT TSAO deriv.?
You can request a quote for 5'-Silyl-2'dT TSAO deriv. directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5'-Silyl-2'dT TSAO deriv.?
Yes, CoreyChem provides custom synthesis services for 5'-Silyl-2'dT TSAO deriv. and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.