(E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one
TL;DR: (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one (CAS 141946-37-4) is a chemical compound with molecular formula C15H12N2O2 and molecular weight 252.08987 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(3E)-5-methoxy-3-(pyridin-2-ylmethylidene)-1H-indol-2-one
Also Known As: 3-[(2-Pyridinyl)methylene]-5-methoxyindolin-2-one, (3E)-5-methoxy-3-(pyridin-2-ylmethylidene)-1H-indol-2-one, (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one, 5-methoxy-3-[(pyridin-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one
Technical Specifications
| Molecular Formula | C15H12N2O2 |
| Molecular Weight | 252.08987 g/mol |
| XLogP | 1.8 |
| Topological Polar Surface Area (TPSA) | 51.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 252.08987 Da |
| Heavy Atoms | 19 |
| Complexity | 380.0 |
| SMILES | COC1=CC\2=C(C=C1)NC(=O)/C2=C/C3=CC=CC=N3 |
| InChIKey | ATKBNIXAZMWUQG-MDWZMJQESA-N |
Chemical Property Profile of (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one
Property Insights of (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one. With a topological polar surface area (TPSA) of 51.2 Ų, (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one?
The CAS number of (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one is 141946-37-4.
What is the molecular formula of (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one?
The molecular formula of (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one is C15H12N2O2.
What is the molecular weight of (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one?
The molecular weight of (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one is 252.08987 g/mol.
Where can I buy (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one?
You can request a quote for (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one?
Yes, CoreyChem provides custom synthesis services for (E)-5-Methoxy-3-(pyridin-2-ylmethylene)indolin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.