Piperazine Dihydrochloride
TL;DR: Piperazine Dihydrochloride (CAS 142-64-3) is a chemical compound with molecular formula C4H12Cl2N2 and molecular weight 158.03775 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
piperazine;dihydrochloride
Also Known As: Piperazine dihydrochloride, Dowzene DHC, Dihydro Pip Wormer, piperazine, Piperazine HCl
Application Areas
Top 5 of 12 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C4H12Cl2N2 |
| Molecular Weight | 158.03775 g/mol |
| XLogP | 0.02 |
| Topological Polar Surface Area (TPSA) | 24.1 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 158.03775 Da |
| Heavy Atoms | 8 |
| Complexity | 26.0 |
| Melting Point | 635 °F (NIOSH, 2024) |
| Solubility | 41 % (NIOSH, 2024) |
| SMILES | C1CNCCN1.Cl.Cl |
| InChIKey | CVVIJWRCGSYCMB-UHFFFAOYSA-N |
Product Description
Applications: Piperazine Dihydrochloride is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Piperazine Dihydrochloride (CAS 142-64-3) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A heterocyclic building block supplied by CoreyChem, Piperazine Dihydrochloride (CAS 142-64-3) has the molecular formula C4H12Cl2N2 and a molecular weight of 158.04 g/mol. Reported properties include a solubility: 41 % (NIOSH, 2024). It is also known as Piperazine dihydrochloride and Dowzene DHC.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Piperazine Dihydrochloride
Property Insights of Piperazine Dihydrochloride
The XLogP value of 0.02 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Piperazine Dihydrochloride. With a topological polar surface area (TPSA) of 24.1 Ų, Piperazine Dihydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Piperazine Dihydrochloride has 4 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Piperazine Dihydrochloride?
The CAS number of Piperazine Dihydrochloride is 142-64-3.
What is the molecular formula of Piperazine Dihydrochloride?
The molecular formula of Piperazine Dihydrochloride is C4H12Cl2N2.
What is the molecular weight of Piperazine Dihydrochloride?
The molecular weight of Piperazine Dihydrochloride is 158.03775 g/mol.
What are the applications of Piperazine Dihydrochloride?
Piperazine Dihydrochloride is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Piperazine Dihydrochloride...
Where can I buy Piperazine Dihydrochloride?
You can request a quote for Piperazine Dihydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Piperazine Dihydrochloride?
Yes, CoreyChem provides custom synthesis services for Piperazine Dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.