Tolfenamic Acid
TL;DR: Tolfenamic Acid (CAS 1420043-61-3) is a chemical compound with molecular formula C14H12ClNO2 and molecular weight 261.05566 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(3-chloro-2-methylanilino)benzoic acid
Also Known As: tolfenamic acid, Clotam, Acido tolfenamico, Acide tolfenamique, Tolfedine
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H12ClNO2 |
| Molecular Weight | 261.05566 g/mol |
| XLogP | 5.2 |
| Topological Polar Surface Area (TPSA) | 49.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 261.05566 Da |
| Heavy Atoms | 18 |
| Complexity | 298.0 |
| SMILES | CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O |
| InChIKey | YEZNLOUZAIOMLT-UHFFFAOYSA-N |
Chemical Property Profile of Tolfenamic Acid
Property Insights of Tolfenamic Acid
The XLogP value of 5.2 indicates that Tolfenamic Acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.3 Ų, Tolfenamic Acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tolfenamic Acid has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Tolfenamic Acid?
The CAS number of Tolfenamic Acid is 1420043-61-3.
What is the molecular formula of Tolfenamic Acid?
The molecular formula of Tolfenamic Acid is C14H12ClNO2.
What is the molecular weight of Tolfenamic Acid?
The molecular weight of Tolfenamic Acid is 261.05566 g/mol.
Where can I buy Tolfenamic Acid?
You can request a quote for Tolfenamic Acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tolfenamic Acid?
Yes, CoreyChem provides custom synthesis services for Tolfenamic Acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.