(E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one
TL;DR: (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one (CAS 1421506-21-9) is a chemical compound with molecular formula C15H9ClFNO and molecular weight 273.03568 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(3E)-5-chloro-3-[(2-fluorophenyl)methylidene]-1H-indol-2-one
Also Known As: AB00749333-01, (3E)-5-chloro-3-[(2-fluorophenyl)methylidene]-1H-indol-2-one, (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one, (3E)-5-chloro-3-[(2-fluorophenyl)methylidene]-2,3-dihydro-1H-indol-2-one
Technical Specifications
| Molecular Formula | C15H9ClFNO |
| Molecular Weight | 273.03568 g/mol |
| XLogP | 3.6 |
| Topological Polar Surface Area (TPSA) | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 273.03568 Da |
| Heavy Atoms | 19 |
| Complexity | 398.0 |
| SMILES | C1=CC=C(C(=C1)/C=C/2\C3=C(C=CC(=C3)Cl)NC2=O)F |
| InChIKey | ZFWPEZWERSHDNS-KPKJPENVSA-N |
Chemical Property Profile of (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one
Property Insights of (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one
The XLogP value of 3.6 indicates that (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one?
The CAS number of (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one is 1421506-21-9.
What is the molecular formula of (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one?
The molecular formula of (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one is C15H9ClFNO.
What is the molecular weight of (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one?
The molecular weight of (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one is 273.03568 g/mol.
Where can I buy (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one?
You can request a quote for (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one?
Yes, CoreyChem provides custom synthesis services for (E)-5-chloro-3-(2-fluoro-benzylidene)-1,3-dihydro-indol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.