(2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid
TL;DR: (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid (CAS 142347-81-7) is a chemical compound with molecular formula C5H9NO3 and molecular weight 131.05824 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid
Also Known As: trans-4-Hydroxy-D-proline, (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid, d-hydroxyproline, H-D-Hyp-OH, L-Hydroxyproline
Application Areas
Top 5 of 12 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C5H9NO3 |
| Molecular Weight | 131.05824 g/mol |
| XLogP | -3.3 |
| Topological Polar Surface Area (TPSA) | 69.6 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 131.05824 Da |
| Heavy Atoms | 9 |
| Complexity | 125.0 |
| SMILES | C1[C@@H](CN[C@H]1C(=O)O)O |
| InChIKey | PMMYEEVYMWASQN-IUYQGCFVSA-N |
Chemical Property Profile of (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid
Property Insights of (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid
The XLogP value of -3.3 indicates that (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 69.6 Ų falls within the moderate polarity range, balancing permeability and solubility for (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid. Following Lipinski's Rule of Five, (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid?
The CAS number of (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid is 142347-81-7.
What is the molecular formula of (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid?
The molecular formula of (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid is C5H9NO3.
What is the molecular weight of (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid?
The molecular weight of (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid is 131.05824 g/mol.
Where can I buy (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid?
You can request a quote for (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid?
Yes, CoreyChem provides custom synthesis services for (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.