2-chloro-5,6-difluoro-1H-benzimidazole
TL;DR: 2-chloro-5,6-difluoro-1H-benzimidazole (CAS 142356-63-6) is a chemical compound with molecular formula C7H3ClF2N2 and molecular weight 187.99529 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-chloro-5,6-difluoro-1H-benzimidazole
Also Known As: 2-chloro-5,6-difluoro-1H-benzimidazole, 2-Chloro-5,6-difluorobenzimidazole, 2-Chloro-5,6-difluoro-1H-benzo[d]imidazole, 1H-Benzimidazole,2-chloro-5,6-difluoro-(9CI), 2-Chloro-5,6difluorobenzimidazole
Application Areas
Top 5 of 3 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C7H3ClF2N2 |
| Molecular Weight | 187.99529 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 28.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 187.99529 Da |
| Heavy Atoms | 12 |
| Complexity | 181.0 |
| SMILES | C1=C2C(=CC(=C1F)F)N=C(N2)Cl |
| InChIKey | VFELEJMYVUPGEO-UHFFFAOYSA-N |
Chemical Property Profile of 2-chloro-5,6-difluoro-1H-benzimidazole
Property Insights of 2-chloro-5,6-difluoro-1H-benzimidazole
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-chloro-5,6-difluoro-1H-benzimidazole. With a topological polar surface area (TPSA) of 28.7 Ų, 2-chloro-5,6-difluoro-1H-benzimidazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-chloro-5,6-difluoro-1H-benzimidazole has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-chloro-5,6-difluoro-1H-benzimidazole?
The CAS number of 2-chloro-5,6-difluoro-1H-benzimidazole is 142356-63-6.
What is the molecular formula of 2-chloro-5,6-difluoro-1H-benzimidazole?
The molecular formula of 2-chloro-5,6-difluoro-1H-benzimidazole is C7H3ClF2N2.
What is the molecular weight of 2-chloro-5,6-difluoro-1H-benzimidazole?
The molecular weight of 2-chloro-5,6-difluoro-1H-benzimidazole is 187.99529 g/mol.
Where can I buy 2-chloro-5,6-difluoro-1H-benzimidazole?
You can request a quote for 2-chloro-5,6-difluoro-1H-benzimidazole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-chloro-5,6-difluoro-1H-benzimidazole?
Yes, CoreyChem provides custom synthesis services for 2-chloro-5,6-difluoro-1H-benzimidazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.