Adiaft
TL;DR: Adiaft (CAS 142545-11-7) is a chemical compound with molecular formula C10H11IN2O4 and molecular weight 349.97635 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2R,4R,5R,6R)-4-(hydroxymethyl)-5-iodo-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one
Also Known As: Adiaft, 2,2'-Anhydro-1-(3'-deoxy-3'-iodoarabinofuranosyl)thymine, (2R,4R,5R,6R)-4-(hydroxymethyl)-5-iodo-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one, 6H-Furo(2',3':4,5)oxazolo(3,2-a)pyrimidin-6-one, 2,3,3a,9a-tetrahydro-2-(hydroxymethyl)-3-iodo-7-methyl-, (2R-(2alpha,3beta,3abeta,9abeta))-, (2R,3R,3aR,9aR)-2-(Hydroxymethyl)-3-iodo-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one
Technical Specifications
| Molecular Formula | C10H11IN2O4 |
| Molecular Weight | 349.97635 g/mol |
| XLogP | 0.3 |
| Topological Polar Surface Area (TPSA) | 71.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 349.97635 Da |
| Heavy Atoms | 17 |
| Complexity | 436.0 |
| SMILES | CC1=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)I)OC2=NC1=O |
| InChIKey | DCTFKMFOWOUYPI-JAGXHNFQSA-N |
Chemical Property Profile of Adiaft
Property Insights of Adiaft
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Adiaft. The TPSA of 71.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Adiaft. Following Lipinski's Rule of Five, Adiaft has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Adiaft?
The CAS number of Adiaft is 142545-11-7.
What is the molecular formula of Adiaft?
The molecular formula of Adiaft is C10H11IN2O4.
What is the molecular weight of Adiaft?
The molecular weight of Adiaft is 349.97635 g/mol.
Where can I buy Adiaft?
You can request a quote for Adiaft directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Adiaft?
Yes, CoreyChem provides custom synthesis services for Adiaft and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.