3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole
TL;DR: 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole (CAS 142623-85-6) is a chemical compound with molecular formula C10H6F4N2 and molecular weight 230.0467 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(4-fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole
Also Known As: 3-(4-fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole, 5-(4-Fluorophenyl)-3-(trifluoromethyl)-1H-pyrazole, SALOR-INT L233056-1EA, 1H-Pyrazole, 3-(4-fluorophenyl)-5-(trifluoromethyl)-, 5-(4-Fluoro-phenyl)-3-trifluoromethyl-1H-pyrazole
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H6F4N2 |
| Molecular Weight | 230.0467 g/mol |
| XLogP | 2.9 |
| Topological Polar Surface Area (TPSA) | 28.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 230.0467 Da |
| Heavy Atoms | 16 |
| Complexity | 235.0 |
| SMILES | C1=CC(=CC=C1C2=NNC(=C2)C(F)(F)F)F |
| InChIKey | NDVPIRBTOQYYHD-UHFFFAOYSA-N |
Chemical Property Profile of 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole
Property Insights of 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole. With a topological polar surface area (TPSA) of 28.7 Ų, 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole?
The CAS number of 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole is 142623-85-6.
What is the molecular formula of 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole?
The molecular formula of 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole is C10H6F4N2.
What is the molecular weight of 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole?
The molecular weight of 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole is 230.0467 g/mol.
Where can I buy 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole?
You can request a quote for 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole?
Yes, CoreyChem provides custom synthesis services for 3-(4-Fluorophenyl)-5-(trifluoromethyl)-1H-pyrazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.