SN-38 carboxylate
TL;DR: SN-38 carboxylate (CAS 142677-15-4) is a chemical compound with molecular formula C22H22N2O6 and molecular weight 410.1478 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S)-2-[12-ethyl-2-hydroxy-8-(hydroxymethyl)-9-oxo-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoic acid
Also Known As: SN-38 carboxylate, Irinotecan Impurity 46, SN-38 carboxylic acid form, Irinotecan Impurity 28, Irinotecan Impurity 54
Technical Specifications
| Molecular Formula | C22H22N2O6 |
| Molecular Weight | 410.1478 g/mol |
| XLogP | 1.2 |
| Topological Polar Surface Area (TPSA) | 131.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 410.1478 Da |
| Heavy Atoms | 30 |
| Complexity | 807.0 |
| SMILES | CCC1=C2CN3C(=CC(=C(C3=O)CO)[C@@](CC)(C(=O)O)O)C2=NC4=C1C=C(C=C4)O |
| InChIKey | IRKZFHZUIBLGKU-QFIPXVFZSA-N |
Chemical Property Profile of SN-38 carboxylate
Property Insights of SN-38 carboxylate
The XLogP value of 1.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for SN-38 carboxylate. The TPSA of 131.0 Ų falls within the moderate polarity range, balancing permeability and solubility for SN-38 carboxylate. Following Lipinski's Rule of Five, SN-38 carboxylate has 4 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of SN-38 carboxylate?
The CAS number of SN-38 carboxylate is 142677-15-4.
What is the molecular formula of SN-38 carboxylate?
The molecular formula of SN-38 carboxylate is C22H22N2O6.
What is the molecular weight of SN-38 carboxylate?
The molecular weight of SN-38 carboxylate is 410.1478 g/mol.
Where can I buy SN-38 carboxylate?
You can request a quote for SN-38 carboxylate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for SN-38 carboxylate?
Yes, CoreyChem provides custom synthesis services for SN-38 carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.