1-(Chloroacetyl)-4-(2-pyridinyl)piperazine
TL;DR: 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine (CAS 143030-54-0) is a chemical compound with molecular formula C11H14ClN3O and molecular weight 239.08253 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-chloro-1-(4-pyridin-2-ylpiperazin-1-yl)ethanone
Also Known As: 4-Descyano-4-bromo-letrozole, 1-(Chloroacetyl)-4-pyridin-2-ylpiperazine, 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine, BAS 08749525, NCI60_004942
Technical Specifications
| Molecular Formula | C11H14ClN3O |
| Molecular Weight | 239.08253 g/mol |
| XLogP | 1.2 |
| Topological Polar Surface Area (TPSA) | 36.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 239.08253 Da |
| Heavy Atoms | 16 |
| Complexity | 241.0 |
| SMILES | C1CN(CCN1C2=CC=CC=N2)C(=O)CCl |
| InChIKey | UMKZSIOUSYFQDQ-UHFFFAOYSA-N |
Chemical Property Profile of 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine
Property Insights of 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine
The XLogP value of 1.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine. With a topological polar surface area (TPSA) of 36.4 Ų, 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine?
The CAS number of 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine is 143030-54-0.
What is the molecular formula of 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine?
The molecular formula of 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine is C11H14ClN3O.
What is the molecular weight of 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine?
The molecular weight of 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine is 239.08253 g/mol.
Where can I buy 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine?
You can request a quote for 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine?
Yes, CoreyChem provides custom synthesis services for 1-(Chloroacetyl)-4-(2-pyridinyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.