6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one
TL;DR: 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one (CAS 143268-80-8) is a chemical compound with molecular formula C11H10FNO2 and molecular weight 207.06955 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-acetyl-8-fluoro-3,4-dihydro-1H-quinolin-2-one
Also Known As: 6-ACETYL-8-FLUORO-3,4-DIHYDROQUINOLIN-2(1H)-ONE, 2(1H)-Quinolinone, 6-acetyl-8-fluoro-3,4-dihydro-, 6-acetyl-3,4-dihydro-8-fluoro-2(1H)-quinolinone, 6-acetyl-8-fluoro-3,4-dihydro-1H-quinolin-2-one
Technical Specifications
| Molecular Formula | C11H10FNO2 |
| Molecular Weight | 207.06955 g/mol |
| XLogP | 0.9 |
| Topological Polar Surface Area (TPSA) | 46.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 207.06955 Da |
| Heavy Atoms | 15 |
| Complexity | 292.0 |
| SMILES | CC(=O)C1=CC2=C(C(=C1)F)NC(=O)CC2 |
| InChIKey | KNKJKJOKKUEFFA-UHFFFAOYSA-N |
Chemical Property Profile of 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one
Property Insights of 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one
The XLogP value of 0.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one. With a topological polar surface area (TPSA) of 46.2 Ų, 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one?
The CAS number of 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one is 143268-80-8.
What is the molecular formula of 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one?
The molecular formula of 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one is C11H10FNO2.
What is the molecular weight of 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one?
The molecular weight of 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one is 207.06955 g/mol.
Where can I buy 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one?
You can request a quote for 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one?
Yes, CoreyChem provides custom synthesis services for 6-Acetyl-8-fluoro-3,4-dihydroquinolin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.