1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride
TL;DR: 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride (CAS 143760-11-6) is a chemical compound with molecular formula C33H38Cl2F2N2OS and molecular weight 618.205 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]-3-naphthalen-1-ylsulfanylpropan-2-ol;dihydrochloride
Also Known As: 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride, 1-Piperazineethanol, 4-(4,4-bis(4-fluorophenyl)butyl)-alpha-((1-naphthalenylthio)methyl)-, dihydrochloride, 1-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]-3-naphthalen-1-ylsulfanylpropan-2-ol dihydrochloride, 1-{4-[4,4-Bis(4-fluorophenyl)butyl]piperazin-1-yl}-3-[(naphthalen-1-yl)sulfanyl]propan-2-ol--hydrogen chloride (1/2)
Technical Specifications
| Molecular Formula | C33H38Cl2F2N2OS |
| Molecular Weight | 618.205 g/mol |
| XLogP | 7.6445 |
| Topological Polar Surface Area (TPSA) | 52.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 11 |
| Exact Mass | 618.205 Da |
| Heavy Atoms | 41 |
| Complexity | 669.0 |
| SMILES | C1CN(CCN1CCCC(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)CC(CSC4=CC=CC5=CC=CC=C54)O.Cl.Cl |
| InChIKey | UVWKOIRGPVYTLQ-UHFFFAOYSA-N |
Chemical Property Profile of 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride
Property Insights of 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride
The XLogP value of 7.6445 indicates that 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.0 Ų, 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride?
The CAS number of 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride is 143760-11-6.
What is the molecular formula of 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride?
The molecular formula of 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride is C33H38Cl2F2N2OS.
What is the molecular weight of 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride?
The molecular weight of 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride is 618.205 g/mol.
Where can I buy 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride?
You can request a quote for 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride?
Yes, CoreyChem provides custom synthesis services for 1-(Bis(4-fluorophenyl)methyl)-4-(2-hydroxy-3-(1-naphthylthio)propyl)piperazine dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.