5-(Trifluoromethyl)pyridine-2-carbonitrile
TL;DR: 5-(Trifluoromethyl)pyridine-2-carbonitrile (CAS 143797-94-8) is a chemical compound with molecular formula C7H3F3N2 and molecular weight 172.02483 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-(trifluoromethyl)pyridine-2-carbonitrile
Also Known As: 5-(trifluoromethyl)picolinonitrile, 5-(trifluoromethyl)pyridine-2-carbonitrile, 2-Cyano-5-(trifluoromethyl)pyridine, -acetonitrile, 2-Cyano-5-trifluoromethylpyridine
Technical Specifications
| Molecular Formula | C7H3F3N2 |
| Molecular Weight | 172.02483 g/mol |
| XLogP | 1.8 |
| Topological Polar Surface Area (TPSA) | 36.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 0 |
| Exact Mass | 172.02483 Da |
| Heavy Atoms | 12 |
| Complexity | 202.0 |
| SMILES | C1=CC(=NC=C1C(F)(F)F)C#N |
| InChIKey | WDSCJULUXJSJOX-UHFFFAOYSA-N |
Chemical Property Profile of 5-(Trifluoromethyl)pyridine-2-carbonitrile
Property Insights of 5-(Trifluoromethyl)pyridine-2-carbonitrile
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-(Trifluoromethyl)pyridine-2-carbonitrile. With a topological polar surface area (TPSA) of 36.7 Ų, 5-(Trifluoromethyl)pyridine-2-carbonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-(Trifluoromethyl)pyridine-2-carbonitrile has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-(Trifluoromethyl)pyridine-2-carbonitrile?
The CAS number of 5-(Trifluoromethyl)pyridine-2-carbonitrile is 143797-94-8.
What is the molecular formula of 5-(Trifluoromethyl)pyridine-2-carbonitrile?
The molecular formula of 5-(Trifluoromethyl)pyridine-2-carbonitrile is C7H3F3N2.
What is the molecular weight of 5-(Trifluoromethyl)pyridine-2-carbonitrile?
The molecular weight of 5-(Trifluoromethyl)pyridine-2-carbonitrile is 172.02483 g/mol.
Where can I buy 5-(Trifluoromethyl)pyridine-2-carbonitrile?
You can request a quote for 5-(Trifluoromethyl)pyridine-2-carbonitrile directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-(Trifluoromethyl)pyridine-2-carbonitrile?
Yes, CoreyChem provides custom synthesis services for 5-(Trifluoromethyl)pyridine-2-carbonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.