Lirequinil
TL;DR: Lirequinil (CAS 143943-73-1) is a chemical compound with molecular formula C26H25ClN2O3 and molecular weight 448.15536 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
10-chloro-1-[(3S)-3-ethoxypyrrolidine-1-carbonyl]-3-phenyl-6,7-dihydrobenzo[a]quinolizin-4-one
Also Known As: Lirequinil, Lirequinilo, Lirequinil [INN], Ro-41-3696, RO41-3696
Technical Specifications
| Molecular Formula | C26H25ClN2O3 |
| Molecular Weight | 448.15536 g/mol |
| XLogP | 3.9 |
| Topological Polar Surface Area (TPSA) | 49.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 448.15536 Da |
| Heavy Atoms | 32 |
| Complexity | 816.0 |
| SMILES | CCO[C@H]1CCN(C1)C(=O)C2=C3C4=C(CCN3C(=O)C(=C2)C5=CC=CC=C5)C=CC(=C4)Cl |
| InChIKey | CBSWRAUYCIIUEI-FQEVSTJZSA-N |
Chemical Property Profile of Lirequinil
Property Insights of Lirequinil
The XLogP value of 3.9 indicates that Lirequinil is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.9 Ų, Lirequinil exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Lirequinil has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Lirequinil?
The CAS number of Lirequinil is 143943-73-1.
What is the molecular formula of Lirequinil?
The molecular formula of Lirequinil is C26H25ClN2O3.
What is the molecular weight of Lirequinil?
The molecular weight of Lirequinil is 448.15536 g/mol.
Where can I buy Lirequinil?
You can request a quote for Lirequinil directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Lirequinil?
Yes, CoreyChem provides custom synthesis services for Lirequinil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.