Fluoroacetic acid
TL;DR: Fluoroacetic acid (CAS 144-49-0) is a chemical compound with molecular formula C2H3FO2 and molecular weight 78.01171 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-fluoroacetic acid
Also Known As: FLUOROACETIC ACID, 2-Fluoroacetic acid, Cymonic acid, Gifblaar poison, Fluoroacetate
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C2H3FO2 |
| Molecular Weight | 78.01171 g/mol |
| XLogP | 0.2 |
| Topological Polar Surface Area (TPSA) | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 78.01171 Da |
| Heavy Atoms | 5 |
| Complexity | 42.0 |
| Melting Point | 95.4 °F (EPA, 1998) |
| Boiling Point | 329 °F at 760 mmHg (EPA, 1998) |
| Density | 1.3693 at 97 °F (EPA, 1998) - Denser than water; will sink |
| Vapor Pressure | 12.8 [mmHg] |
| Refractive Index | Mobile liquid, fp: -32 °C. Practically odorless or faint, fruit-like odor. Specific gravity: 1.1744 at 20 dg C/4 °C; 1.1613 at 15 °C/4 °C. Index of refraction: 1.3678 at 20 °C/D. Soluble in water; slightly soluble in petroleum ether /Fluoroacetic acid, methyl ester/ |
| Solubility | Miscible with water (1.0X10+6 mg/L) at 25 °C |
| SMILES | C(C(=O)O)F |
| InChIKey | QEWYKACRFQMRMB-UHFFFAOYSA-N |
Product Description
Applications: Fluoroacetic acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Fluoroacetic acid (CAS 144-49-0) is a pharmaceutical intermediate with the molecular formula C2H3FO2 and a molecular weight of 78.01 g/mol. Key physical properties include a density of 1.3693 at 97 °F (EPA, 1998) - Denser than water; will sink g/cm³, a solubility: Miscible with water (1.0X10+6 mg/L) at 25 °C. Synonyms include FLUOROACETIC ACID and 2-Fluoroacetic acid.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Fluoroacetic acid
Property Insights of Fluoroacetic acid
The XLogP value of 0.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Fluoroacetic acid. With a topological polar surface area (TPSA) of 37.3 Ų, Fluoroacetic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Fluoroacetic acid has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Fluoroacetic acid?
The CAS number of Fluoroacetic acid is 144-49-0.
What is the molecular formula of Fluoroacetic acid?
The molecular formula of Fluoroacetic acid is C2H3FO2.
What is the molecular weight of Fluoroacetic acid?
The molecular weight of Fluoroacetic acid is 78.01171 g/mol.
What are the applications of Fluoroacetic acid?
Fluoroacetic acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Fluoroacetic acid?
You can request a quote for Fluoroacetic acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Fluoroacetic acid?
Yes, CoreyChem provides custom synthesis services for Fluoroacetic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.