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Sulfacetamide structure
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Sulfacetamide

TL;DR: Sulfacetamide (CAS 144-80-9) is a chemical compound with molecular formula C8H10N2O3S and molecular weight 214.04121 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.

N-(4-aminophenyl)sulfonylacetamide

Also Known As: sulfacetamide, Sulphacetamide, Acetosulfamine, Urosulfon, Acetosulfamin

CAS Number
144-80-9
Molecular Formula
C8H10N2O3S
Molecular Weight
214.04121 g/mol
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Application Areas

Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.

Agrochemicals (47 patents) Analytical Reagents (93 patents) Biotechnology (264 patents) Catalysts (15 patents) Coatings & Adhesives (25 patents)

Technical Specifications

Molecular FormulaC8H10N2O3S
Molecular Weight214.04121 g/mol
XLogP-1.0
Topological Polar Surface Area (TPSA)97.6 Ų
Hydrogen Bond Donors2
Hydrogen Bond Acceptors4
Rotatable Bonds2
Exact Mass214.04121 Da
Heavy Atoms14
Complexity299.0
Melting Point360 to 363 °F (NTP, 1992)
Solubilityless than 0.1 mg/mL at 61 °F (NTP, 1992)
SMILESCC(=O)NS(=O)(=O)C1=CC=C(C=C1)N
InChIKeySKIVFJLNDNKQPD-UHFFFAOYSA-N

Product Description

Applications: Sulfacetamide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Sulfacetamide (CAS 144-80-9) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.

A pharmaceutical intermediate supplied by CoreyChem, Sulfacetamide (CAS 144-80-9) has the molecular formula C8H10N2O3S and a molecular weight of 214.04 g/mol. Reported properties include a solubility: less than 0.1 mg/mL at 61 °F (NTP, 1992). It is also known as sulfacetamide and Sulphacetamide.

Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.

Chemical Property Profile of Sulfacetamide

XLogP
-1.0
TPSA (Topological Polar Surface Area)
97.6
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
14
Complexity
299.0
Exact Mass
214.04121
Monoisotopic Mass
214.04121
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Sulfacetamide

The XLogP value of -1.0 indicates that Sulfacetamide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 97.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Sulfacetamide. Following Lipinski's Rule of Five, Sulfacetamide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the CAS number of Sulfacetamide?

The CAS number of Sulfacetamide is 144-80-9.

What is the molecular formula of Sulfacetamide?

The molecular formula of Sulfacetamide is C8H10N2O3S.

What is the molecular weight of Sulfacetamide?

The molecular weight of Sulfacetamide is 214.04121 g/mol.

What are the applications of Sulfacetamide?

Sulfacetamide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Sulfacetamide (CAS 144-80-9) with custom...

Where can I buy Sulfacetamide?

You can request a quote for Sulfacetamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.

Does CoreyChem offer custom synthesis for Sulfacetamide?

Yes, CoreyChem provides custom synthesis services for Sulfacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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