Sulfamethizole
TL;DR: Sulfamethizole (CAS 144-82-1) is a chemical compound with molecular formula C9H10N4O2S2 and molecular weight 270.0245 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
Also Known As: sulfamethizole, Sulfamethizol, Sulphamethizole, Thiosulfil, Rufol
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H10N4O2S2 |
| Molecular Weight | 270.0245 g/mol |
| XLogP | 0.5 |
| Topological Polar Surface Area (TPSA) | 135.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 270.0245 Da |
| Heavy Atoms | 17 |
| Complexity | 348.0 |
| Melting Point | 406 °F (NTP, 1992) |
| Solubility | Insoluble at pH 6.5 (=10mg/ml). (NTP, 1992) |
| SMILES | CC1=NN=C(S1)NS(=O)(=O)C2=CC=C(C=C2)N |
| InChIKey | VACCAVUAMIDAGB-UHFFFAOYSA-N |
Product Description
Applications: Sulfamethizole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Sulfamethizole (CAS 144-82-1) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Sulfamethizole is a pharmaceutical intermediate identified by CAS number 144-82-1 and the molecular formula C9H10N4O2S2 and a molecular weight of 270.02 g/mol. Physically, the compound has a solubility: Insoluble at pH 6.5 (=10mg/ml). (NTP, 1992). It is also known as sulfamethizole and Sulfamethizol.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Sulfamethizole
Property Insights of Sulfamethizole
The XLogP value of 0.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Sulfamethizole. The TPSA of 135.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Sulfamethizole. Following Lipinski's Rule of Five, Sulfamethizole has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Sulfamethizole?
The CAS number of Sulfamethizole is 144-82-1.
What is the molecular formula of Sulfamethizole?
The molecular formula of Sulfamethizole is C9H10N4O2S2.
What is the molecular weight of Sulfamethizole?
The molecular weight of Sulfamethizole is 270.0245 g/mol.
What are the applications of Sulfamethizole?
Sulfamethizole is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Sulfamethizole (CAS 144-82-1) with...
Where can I buy Sulfamethizole?
You can request a quote for Sulfamethizole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Sulfamethizole?
Yes, CoreyChem provides custom synthesis services for Sulfamethizole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.