Rizatriptan
TL;DR: Rizatriptan (CAS 144034-80-0) is a chemical compound with molecular formula C15H19N5 and molecular weight 269.16403 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine
Also Known As: rizatriptan, Risatriptan, Rizatriptan benzoate, MK 462 free base, rizatriptanum
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H19N5 |
| Molecular Weight | 269.16403 g/mol |
| XLogP | 1.7 |
| Topological Polar Surface Area (TPSA) | 49.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 269.16403 Da |
| Heavy Atoms | 20 |
| Complexity | 309.0 |
| Melting Point | 178-180 |
| Solubility | 42 |
| SMILES | CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3 |
| InChIKey | ULFRLSNUDGIQQP-UHFFFAOYSA-N |
Product Description
Applications: Rizatriptan is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Rizatriptan (CAS 144034-80-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Rizatriptan (CAS 144034-80-0) has the molecular formula C15H19N5 and a molecular weight of 269.16 g/mol. Reported properties include a solubility: 42. It is also known as rizatriptan and Risatriptan.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Rizatriptan
Property Insights of Rizatriptan
The XLogP value of 1.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Rizatriptan. With a topological polar surface area (TPSA) of 49.7 Ų, Rizatriptan exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Rizatriptan has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Rizatriptan?
The CAS number of Rizatriptan is 144034-80-0.
What is the molecular formula of Rizatriptan?
The molecular formula of Rizatriptan is C15H19N5.
What is the molecular weight of Rizatriptan?
The molecular weight of Rizatriptan is 269.16403 g/mol.
What are the applications of Rizatriptan?
Rizatriptan is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Rizatriptan (CAS 144034-80-0) with custom...
Where can I buy Rizatriptan?
You can request a quote for Rizatriptan directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Rizatriptan?
Yes, CoreyChem provides custom synthesis services for Rizatriptan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.