1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine
TL;DR: 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine (CAS 144410-24-2) is a chemical compound with molecular formula C17H24N2O3SSi and molecular weight 364.1277 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-methyl-6-phenylsulfanyl-1-(2-trimethylsilylethoxymethyl)pyrimidine-2,4-dione
Also Known As: HEPT deriv., 1-Me3SiEtOMe-6PhS T, 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine, 1-[[2-(Trimethylsilyl)ethoxy]methyl]-6-(phenylthio)thymine, 1-[2-[(TrimethylSilyl)ethoxy]methyl]-6-(phenylthio)thymine
Technical Specifications
| Molecular Formula | C17H24N2O3SSi |
| Molecular Weight | 364.1277 g/mol |
| XLogP | 3.30852 |
| Topological Polar Surface Area (TPSA) | 83.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Exact Mass | 364.1277 Da |
| Heavy Atoms | 24 |
| Complexity | 510.0 |
| SMILES | CC1=C(N(C(=O)NC1=O)COCC[Si](C)(C)C)SC2=CC=CC=C2 |
| InChIKey | XHCKCIDCEXXYHT-UHFFFAOYSA-N |
Chemical Property Profile of 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine
Property Insights of 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine
The XLogP value of 3.30852 indicates that 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 83.9 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine. Following Lipinski's Rule of Five, 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine?
The CAS number of 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine is 144410-24-2.
What is the molecular formula of 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine?
The molecular formula of 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine is C17H24N2O3SSi.
What is the molecular weight of 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine?
The molecular weight of 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine is 364.1277 g/mol.
Where can I buy 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine?
You can request a quote for 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine?
Yes, CoreyChem provides custom synthesis services for 1-(2-((TrimethylSilyl)ethoxy)methyl)-6-(phenylthio)thymine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.