GR 92549
TL;DR: GR 92549 (CAS 144501-27-9) is a chemical compound with molecular formula C25H26F2N2O4 and molecular weight 456.18607 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(E,3S,5R)-7-[4,5-bis(4-fluorophenyl)-2-propan-2-ylimidazol-1-yl]-3,5-dihydroxyhept-6-enoic acid
Also Known As: GR 92549, GR95030X, 3,5-Dihydroxy-7-(4,5-bis(4-fluorophenyl)-2-(1-methylethyl)-1H-imidazol-1-yl)-6-heptenoic acid, (E,3S,5R)-7-[4,5-bis(4-fluorophenyl)-2-propan-2-ylimidazol-1-yl]-3,5-dihydroxyhept-6-enoic acid, (3S,5R,6E)-7-[4,5-bis(4-fluorophenyl)-2-(propan-2-yl)-1H-imidazol-1-yl]-3,5-dihydroxyhept-6-enoic acid
Technical Specifications
| Molecular Formula | C25H26F2N2O4 |
| Molecular Weight | 456.18607 g/mol |
| XLogP | 3.5 |
| Topological Polar Surface Area (TPSA) | 95.6 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 9 |
| Exact Mass | 456.18607 Da |
| Heavy Atoms | 33 |
| Complexity | 648.0 |
| SMILES | CC(C)C1=NC(=C(N1/C=C/[C@@H](C[C@@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=C(C=C3)F |
| InChIKey | GQOQQDINYJTQDY-GOHIESPPSA-N |
Chemical Property Profile of GR 92549
Property Insights of GR 92549
The XLogP value of 3.5 indicates that GR 92549 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 95.6 Ų falls within the moderate polarity range, balancing permeability and solubility for GR 92549. Following Lipinski's Rule of Five, GR 92549 has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of GR 92549?
The CAS number of GR 92549 is 144501-27-9.
What is the molecular formula of GR 92549?
The molecular formula of GR 92549 is C25H26F2N2O4.
What is the molecular weight of GR 92549?
The molecular weight of GR 92549 is 456.18607 g/mol.
Where can I buy GR 92549?
You can request a quote for GR 92549 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for GR 92549?
Yes, CoreyChem provides custom synthesis services for GR 92549 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.