4-(Trifluoroacetamido)-3-isoxazolidone
TL;DR: 4-(Trifluoroacetamido)-3-isoxazolidone (CAS 144533-21-1) is a chemical compound with molecular formula C5H5F3N2O3 and molecular weight 198.02522 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,2,2-trifluoro-N-(3-oxo-1,2-oxazolidin-4-yl)acetamide
Also Known As: Cycloserine analog, 4-(Trifluoroacetamido)-3-isoxazolidone, D-4-(trifluoroacetamido)-3-isoxazolidone, N-[(3-Oxoisoxazolidin)-4-yl]trifluoroacetamide, 2,2,2-trifluoro-N-(3-oxo-1,2-oxazolidin-4-yl)acetamide
Technical Specifications
| Molecular Formula | C5H5F3N2O3 |
| Molecular Weight | 198.02522 g/mol |
| XLogP | -0.1 |
| Topological Polar Surface Area (TPSA) | 67.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 198.02522 Da |
| Heavy Atoms | 13 |
| Complexity | 240.0 |
| SMILES | C1C(C(=O)NO1)NC(=O)C(F)(F)F |
| InChIKey | ZPKKJDVNJQFYEW-UHFFFAOYSA-N |
Chemical Property Profile of 4-(Trifluoroacetamido)-3-isoxazolidone
Property Insights of 4-(Trifluoroacetamido)-3-isoxazolidone
The XLogP value of -0.1 indicates that 4-(Trifluoroacetamido)-3-isoxazolidone is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 67.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(Trifluoroacetamido)-3-isoxazolidone. Following Lipinski's Rule of Five, 4-(Trifluoroacetamido)-3-isoxazolidone has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-(Trifluoroacetamido)-3-isoxazolidone?
The CAS number of 4-(Trifluoroacetamido)-3-isoxazolidone is 144533-21-1.
What is the molecular formula of 4-(Trifluoroacetamido)-3-isoxazolidone?
The molecular formula of 4-(Trifluoroacetamido)-3-isoxazolidone is C5H5F3N2O3.
What is the molecular weight of 4-(Trifluoroacetamido)-3-isoxazolidone?
The molecular weight of 4-(Trifluoroacetamido)-3-isoxazolidone is 198.02522 g/mol.
Where can I buy 4-(Trifluoroacetamido)-3-isoxazolidone?
You can request a quote for 4-(Trifluoroacetamido)-3-isoxazolidone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-(Trifluoroacetamido)-3-isoxazolidone?
Yes, CoreyChem provides custom synthesis services for 4-(Trifluoroacetamido)-3-isoxazolidone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.