3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one
TL;DR: 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one (CAS 144603-83-8) is a chemical compound with molecular formula C9H5ClFNO2 and molecular weight 212.99928 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-chloro-3-fluoro-1H-quinoline-2,4-dione
Also Known As: 3-chloro-3-fluoro-1H-quinoline-2,4-dione, 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one
Technical Specifications
| Molecular Formula | C9H5ClFNO2 |
| Molecular Weight | 212.99928 g/mol |
| XLogP | 1.8 |
| Topological Polar Surface Area (TPSA) | 46.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 212.99928 Da |
| Heavy Atoms | 14 |
| Complexity | 297.0 |
| SMILES | C1=CC=C2C(=C1)C(=O)C(C(=O)N2)(F)Cl |
| InChIKey | MMJJDKQFBVGICO-UHFFFAOYSA-N |
Chemical Property Profile of 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one
Property Insights of 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one. With a topological polar surface area (TPSA) of 46.2 Ų, 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one?
The CAS number of 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one is 144603-83-8.
What is the molecular formula of 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one?
The molecular formula of 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one is C9H5ClFNO2.
What is the molecular weight of 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one?
The molecular weight of 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one is 212.99928 g/mol.
Where can I buy 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one?
You can request a quote for 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one?
Yes, CoreyChem provides custom synthesis services for 3-Chloro-3-fluoro-2-hydroxyquinolin-4(3H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.