20alpha-Dihydroprogesterone
TL;DR: 20alpha-Dihydroprogesterone (CAS 145-14-2) is a chemical compound with molecular formula C21H32O2 and molecular weight 316.24023 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(8S,9S,10R,13S,14S,17S)-17-[(1S)-1-hydroxyethyl]-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Also Known As: Dihydrogesterone, DIHYDROPROGESTERONE, 20(S)-Hydroxyprogesterone, 20alpha-Dihydroprogesterone, 20-alpha-Progerol
Application Areas
Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H32O2 |
| Molecular Weight | 316.24023 g/mol |
| XLogP | 4.2 |
| Topological Polar Surface Area (TPSA) | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 316.24023 Da |
| Heavy Atoms | 23 |
| Complexity | 550.0 |
| Melting Point | 126 - 131 °C |
| SMILES | C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O |
| InChIKey | RWBRUCCWZPSBFC-RXRZZTMXSA-N |
Product Description
Applications: 20alpha-Dihydroprogesterone is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 20alpha-Dihydroprogesterone (CAS 145-14-2) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, 20alpha-Dihydroprogesterone (CAS 145-14-2) has the molecular formula C21H32O2 and a molecular weight of 316.24 g/mol. It is also known as Dihydrogesterone and DIHYDROPROGESTERONE.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 20alpha-Dihydroprogesterone
Property Insights of 20alpha-Dihydroprogesterone
The XLogP value of 4.2 indicates that 20alpha-Dihydroprogesterone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, 20alpha-Dihydroprogesterone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 20alpha-Dihydroprogesterone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 20alpha-Dihydroprogesterone?
The CAS number of 20alpha-Dihydroprogesterone is 145-14-2.
What is the molecular formula of 20alpha-Dihydroprogesterone?
The molecular formula of 20alpha-Dihydroprogesterone is C21H32O2.
What is the molecular weight of 20alpha-Dihydroprogesterone?
The molecular weight of 20alpha-Dihydroprogesterone is 316.24023 g/mol.
What are the applications of 20alpha-Dihydroprogesterone?
20alpha-Dihydroprogesterone is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 20alpha-Dihydroprogesterone (CAS 145-14-2) with...
Where can I buy 20alpha-Dihydroprogesterone?
You can request a quote for 20alpha-Dihydroprogesterone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 20alpha-Dihydroprogesterone?
Yes, CoreyChem provides custom synthesis services for 20alpha-Dihydroprogesterone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.