![2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine structure](/static/products/1451/145143-27-7.webp)
2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine
TL;DR: 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine (CAS 145143-27-7) is a chemical compound with molecular formula C7H5ClF3NS and molecular weight 226.97833 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(1-chloro-2,2,2-trifluoroethyl)sulfanylpyridine
Also Known As: 2-[(1-chloro-2,2,2-trifluoroethyl)thio]pyridine, 2-[(1-chloro-2,2,2-trifluoroethyl)sulfanyl]pyridine, 2-((1-Chloro-2,2,2-trifluoroethyl)thio)pyridine, J3.446.683A, 2-(1-chloro-2,2,2-trifluoro-ethyl)sulfanylpyridine
Technical Specifications
| Molecular Formula | C7H5ClF3NS |
| Molecular Weight | 226.97833 g/mol |
| XLogP | 3.6 |
| Topological Polar Surface Area (TPSA) | 38.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 226.97833 Da |
| Heavy Atoms | 13 |
| Complexity | 164.0 |
| SMILES | C1=CC=NC(=C1)SC(C(F)(F)F)Cl |
| InChIKey | HLTBONPVFIBKGI-UHFFFAOYSA-N |
Chemical Property Profile of 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine
Property Insights of 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine
The XLogP value of 3.6 indicates that 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.2 Ų, 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine?
The CAS number of 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine is 145143-27-7.
What is the molecular formula of 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine?
The molecular formula of 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine is C7H5ClF3NS.
What is the molecular weight of 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine?
The molecular weight of 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine is 226.97833 g/mol.
Where can I buy 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine?
You can request a quote for 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine?
Yes, CoreyChem provides custom synthesis services for 2-[(1-Chloro-2,2,2-trifluoroethyl)thio]pyridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.