1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine
TL;DR: 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine (CAS 145253-76-5) is a chemical compound with molecular formula C16H18N2O2S and molecular weight 302.1089 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[4-(2-methoxyphenyl)piperazin-1-yl]-thiophen-2-ylmethanone
Also Known As: Maybridge1_004085, 1-(2-methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine, JFD 01728, 4-(2-methoxyphenyl)piperazinyl 2-thienyl ketone, BAS 00624703
Application Areas
Top 5 of 1 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H18N2O2S |
| Molecular Weight | 302.1089 g/mol |
| XLogP | 3.0 |
| Topological Polar Surface Area (TPSA) | 61.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 302.1089 Da |
| Heavy Atoms | 21 |
| Complexity | 358.0 |
| SMILES | COC1=CC=CC=C1N2CCN(CC2)C(=O)C3=CC=CS3 |
| InChIKey | OQQADZFNFNHIJO-UHFFFAOYSA-N |
Chemical Property Profile of 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine
Property Insights of 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine
The XLogP value of 3.0 indicates that 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine. Following Lipinski's Rule of Five, 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine?
The CAS number of 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine is 145253-76-5.
What is the molecular formula of 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine?
The molecular formula of 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine is C16H18N2O2S.
What is the molecular weight of 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine?
The molecular weight of 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine is 302.1089 g/mol.
Where can I buy 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine?
You can request a quote for 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine?
Yes, CoreyChem provides custom synthesis services for 1-(2-Methoxyphenyl)-4-(thiophene-2-carbonyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.