Tetomilast
TL;DR: Tetomilast (CAS 145739-56-6) is a chemical compound with molecular formula C19H18N2O4S and molecular weight 370.09872 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid
Also Known As: Tetomilast, tetomilastum, Tetomilast [INN], 6-(2-(3,4-Diethoxyphenyl)thiazol-4-yl)picolinic acid, Tetomilast (OPC6535)
Technical Specifications
| Molecular Formula | C19H18N2O4S |
| Molecular Weight | 370.09872 g/mol |
| XLogP | 3.8 |
| Topological Polar Surface Area (TPSA) | 110.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 370.09872 Da |
| Heavy Atoms | 26 |
| Complexity | 467.0 |
| SMILES | CCOC1=C(C=C(C=C1)C2=NC(=CS2)C3=NC(=CC=C3)C(=O)O)OCC |
| InChIKey | XDBHURGONHZNJF-UHFFFAOYSA-N |
Chemical Property Profile of Tetomilast
Property Insights of Tetomilast
The XLogP value of 3.8 indicates that Tetomilast is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 110.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Tetomilast. Following Lipinski's Rule of Five, Tetomilast has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Tetomilast?
The CAS number of Tetomilast is 145739-56-6.
What is the molecular formula of Tetomilast?
The molecular formula of Tetomilast is C19H18N2O4S.
What is the molecular weight of Tetomilast?
The molecular weight of Tetomilast is 370.09872 g/mol.
Where can I buy Tetomilast?
You can request a quote for Tetomilast directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tetomilast?
Yes, CoreyChem provides custom synthesis services for Tetomilast and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.