CGP 53353
TL;DR: CGP 53353 (CAS 145915-60-2) is a chemical compound with molecular formula C20H13F2N3O2 and molecular weight 365.0976 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5,6-bis(4-fluoroanilino)isoindole-1,3-dione
Also Known As: CGP 53353, DAPH 2, PKCbetaII/EGFR Inhibitor, DAPH 7, PKCbII/EGFR Inhibitor
Technical Specifications
| Molecular Formula | C20H13F2N3O2 |
| Molecular Weight | 365.0976 g/mol |
| XLogP | 4.0 |
| Topological Polar Surface Area (TPSA) | 70.2 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 365.0976 Da |
| Heavy Atoms | 27 |
| Complexity | 511.0 |
| SMILES | C1=CC(=CC=C1NC2=C(C=C3C(=C2)C(=O)NC3=O)NC4=CC=C(C=C4)F)F |
| InChIKey | RONQPWQYDRPRGG-UHFFFAOYSA-N |
Chemical Property Profile of CGP 53353
Property Insights of CGP 53353
The XLogP value of 4.0 indicates that CGP 53353 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.2 Ų falls within the moderate polarity range, balancing permeability and solubility for CGP 53353. Following Lipinski's Rule of Five, CGP 53353 has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of CGP 53353?
The CAS number of CGP 53353 is 145915-60-2.
What is the molecular formula of CGP 53353?
The molecular formula of CGP 53353 is C20H13F2N3O2.
What is the molecular weight of CGP 53353?
The molecular weight of CGP 53353 is 365.0976 g/mol.
Where can I buy CGP 53353?
You can request a quote for CGP 53353 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for CGP 53353?
Yes, CoreyChem provides custom synthesis services for CGP 53353 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.