2-Chloroadenosine
TL;DR: 2-Chloroadenosine (CAS 146-77-0) is a chemical compound with molecular formula C10H12ClN5O4 and molecular weight 301.05777 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2R,3R,4S,5R)-2-(6-amino-2-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Also Known As: 2-Chloroadenosine, ADENOSINE, 2-CHLORO-, Chloroadenosine, 2 Chloroadenosine, 5-Chloroformycin A
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H12ClN5O4 |
| Molecular Weight | 301.05777 g/mol |
| XLogP | -0.1 |
| Topological Polar Surface Area (TPSA) | 140.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 301.05777 Da |
| Heavy Atoms | 20 |
| Complexity | 367.0 |
| Solubility | >45.3 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | C1=NC2=C(N=C(N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)Cl)N |
| InChIKey | BIXYYZIIJIXVFW-UUOKFMHZSA-N |
Product Description
Applications: 2-Chloroadenosine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2-Chloroadenosine (CAS 146-77-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
2-Chloroadenosine is a pharmaceutical intermediate identified by CAS number 146-77-0 and the molecular formula C10H12ClN5O4 and a molecular weight of 301.06 g/mol. Physically, the compound has a solubility: >45.3 [ug/mL] (The mean of the results at pH 7.4). It is also known as 2-Chloroadenosine and ADENOSINE, 2-CHLORO-.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 2-Chloroadenosine
Property Insights of 2-Chloroadenosine
The XLogP value of -0.1 indicates that 2-Chloroadenosine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 140.0 Ų indicates high polarity, suggesting 2-Chloroadenosine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 2-Chloroadenosine has 4 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-Chloroadenosine?
The CAS number of 2-Chloroadenosine is 146-77-0.
What is the molecular formula of 2-Chloroadenosine?
The molecular formula of 2-Chloroadenosine is C10H12ClN5O4.
What is the molecular weight of 2-Chloroadenosine?
The molecular weight of 2-Chloroadenosine is 301.05777 g/mol.
What are the applications of 2-Chloroadenosine?
2-Chloroadenosine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2-Chloroadenosine (CAS 146-77-0) with...
Where can I buy 2-Chloroadenosine?
You can request a quote for 2-Chloroadenosine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-Chloroadenosine?
Yes, CoreyChem provides custom synthesis services for 2-Chloroadenosine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.