2-Fluoroadenosine
TL;DR: 2-Fluoroadenosine (CAS 146-78-1) is a chemical compound with molecular formula C10H12FN5O4 and molecular weight 285.08734 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2R,3R,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Also Known As: 2-Fluoroadenosine, ADENOSINE, 2-FLUORO-, 2-FluoroAdo, 2-Far, 2-Fas
Application Areas
Top 5 of 8 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H12FN5O4 |
| Molecular Weight | 285.08734 g/mol |
| XLogP | -0.6 |
| Topological Polar Surface Area (TPSA) | 140.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 2 |
| Exact Mass | 285.08734 Da |
| Heavy Atoms | 20 |
| Complexity | 367.0 |
| Solubility | >42.8 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | C1=NC2=C(N=C(N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)F)N |
| InChIKey | HBUBKKRHXORPQB-UUOKFMHZSA-N |
Product Description
Applications: 2-Fluoroadenosine is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A heterocyclic building block supplied by CoreyChem, 2-Fluoroadenosine (CAS 146-78-1) has the molecular formula C10H12FN5O4 and a molecular weight of 285.09 g/mol. Reported properties include a solubility: >42.8 [ug/mL] (The mean of the results at pH 7.4). Synonyms include 2-Fluoroadenosine and ADENOSINE, 2-FLUORO-.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 2-Fluoroadenosine
Property Insights of 2-Fluoroadenosine
The XLogP value of -0.6 indicates that 2-Fluoroadenosine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 140.0 Ų indicates high polarity, suggesting 2-Fluoroadenosine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 2-Fluoroadenosine has 4 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-Fluoroadenosine?
The CAS number of 2-Fluoroadenosine is 146-78-1.
What is the molecular formula of 2-Fluoroadenosine?
The molecular formula of 2-Fluoroadenosine is C10H12FN5O4.
What is the molecular weight of 2-Fluoroadenosine?
The molecular weight of 2-Fluoroadenosine is 285.08734 g/mol.
What are the applications of 2-Fluoroadenosine?
2-Fluoroadenosine is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy 2-Fluoroadenosine?
You can request a quote for 2-Fluoroadenosine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-Fluoroadenosine?
Yes, CoreyChem provides custom synthesis services for 2-Fluoroadenosine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.