TL;DR: neurotrophin 4/5 (CAS 146318-03-8) is a chemical compound with molecular formula C15H24N5O16P3 and molecular weight 623.0431 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4S)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
Also Known As: neurotrophin 4/5, HUMAN NEUROTROPHIC 4/5, nadp nicotinamide-adenine-dinucleotide phosphate, [(2r,3r,4r,5r)-5-(6-Amino-9h-Purin-9-Yl)-3-Hydroxy-4-(Phosphonooxy)tetrahydrofuran-2-Yl]methyl [(2r,3s,4s)-3,4-Dihydroxytetrahydrofuran-2-Yl]methyl Dihydrogen Diphosphate, [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4S)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
| Molecular Formula | C15H24N5O16P3 |
| Molecular Weight | 623.0431 g/mol |
| XLogP | -6.7 |
| Topological Polar Surface Area (TPSA) | 318.0 Ų |
| Hydrogen Bond Donors | 8 |
| Hydrogen Bond Acceptors | 20 |
| Rotatable Bonds | 11 |
| Exact Mass | 623.0431 Da |
| Heavy Atoms | 39 |
| Complexity | 1010.0 |
| SMILES | C1[C@@H]([C@@H]([C@H](O1)COP(=O)(O)OP(=O)(O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)OP(=O)(O)O)O)O)O |
| InChIKey | XDDBFIXGEVGCEU-AOOZFPJJSA-N |
The XLogP value of -6.7 indicates that neurotrophin 4/5 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 318.0 Ų indicates high polarity, suggesting neurotrophin 4/5 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, neurotrophin 4/5 has 8 hydrogen bond donor(s) and 20 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
The CAS number of neurotrophin 4/5 is 146318-03-8.
The molecular formula of neurotrophin 4/5 is C15H24N5O16P3.
The molecular weight of neurotrophin 4/5 is 623.0431 g/mol.
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