4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one
TL;DR: 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one (CAS 146801-21-0) is a chemical compound with molecular formula C14H11F3O2S and molecular weight 300.04318 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4,4,4-trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one
Also Known As: 4,4,4-trifluoro-3-hydroxy-3-phenyl-1-(thiophen-2-yl)butan-1-one, 4,4,4-trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one, 4,4,4-trifluoro-3-hydroxy-3-phenyl-1-(2-thienyl)-1-butanone, 4,4,4-trifluoro-3-hydroxy-3-phenyl-1-(2-thienyl)butan-1-one, 4,4,4-trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-yl-1-butanone
Technical Specifications
| Molecular Formula | C14H11F3O2S |
| Molecular Weight | 300.04318 g/mol |
| XLogP | 3.3 |
| Topological Polar Surface Area (TPSA) | 65.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 300.04318 Da |
| Heavy Atoms | 20 |
| Complexity | 353.0 |
| SMILES | C1=CC=C(C=C1)C(CC(=O)C2=CC=CS2)(C(F)(F)F)O |
| InChIKey | DRBLFYFYWKRWMI-UHFFFAOYSA-N |
Chemical Property Profile of 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one
Property Insights of 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one
The XLogP value of 3.3 indicates that 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.5 Ų falls within the moderate polarity range, balancing permeability and solubility for 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one. Following Lipinski's Rule of Five, 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one?
The CAS number of 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one is 146801-21-0.
What is the molecular formula of 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one?
The molecular formula of 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one is C14H11F3O2S.
What is the molecular weight of 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one?
The molecular weight of 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one is 300.04318 g/mol.
Where can I buy 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one?
You can request a quote for 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one?
Yes, CoreyChem provides custom synthesis services for 4,4,4-Trifluoro-3-hydroxy-3-phenyl-1-thiophen-2-ylbutan-1-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.