(3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one
TL;DR: (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one (CAS 146924-91-6) is a chemical compound with molecular formula C16H15NO3 and molecular weight 269.1052 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one
Also Known As: Docetaxel Impurity 19, Docetaxel Impurity 91, starbld0008010, (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one, 1-(p-Anisyl)-3beta-hydroxy-4beta-phenylazetidin-2-one
Technical Specifications
| Molecular Formula | C16H15NO3 |
| Molecular Weight | 269.1052 g/mol |
| XLogP | 1.9 |
| Topological Polar Surface Area (TPSA) | 49.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 269.1052 Da |
| Heavy Atoms | 20 |
| Complexity | 346.0 |
| SMILES | COC1=CC=C(C=C1)N2[C@@H]([C@@H](C2=O)O)C3=CC=CC=C3 |
| InChIKey | FTOHXQPVCMMHRO-CABCVRRESA-N |
Chemical Property Profile of (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one
Property Insights of (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one
The XLogP value of 1.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one. With a topological polar surface area (TPSA) of 49.8 Ų, (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one?
The CAS number of (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one is 146924-91-6.
What is the molecular formula of (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one?
The molecular formula of (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one is C16H15NO3.
What is the molecular weight of (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one?
The molecular weight of (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one is 269.1052 g/mol.
Where can I buy (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one?
You can request a quote for (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one?
Yes, CoreyChem provides custom synthesis services for (3S,4R)-3-hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.