Diphenhydramine Hydrochloride
TL;DR: Diphenhydramine Hydrochloride (CAS 147-24-0) is a chemical compound with molecular formula C17H22ClNO and molecular weight 291.13898 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-benzhydryloxy-N,N-dimethylethanamine;hydrochloride
Also Known As: DIPHENHYDRAMINE HYDROCHLORIDE, Diphenhydramine HCl, Benadryl, Dimedrol, Allergival
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H22ClNO |
| Molecular Weight | 291.13898 g/mol |
| XLogP | 3.78 |
| Topological Polar Surface Area (TPSA) | 12.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 6 |
| Exact Mass | 291.13898 Da |
| Heavy Atoms | 20 |
| Complexity | 211.0 |
| Melting Point | 331 to 338 °F (NTP, 1992) |
| Solubility | greater than or equal to 100 mg/mL at 70.7 °F (NTP, 1992) |
| SMILES | CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl |
| InChIKey | PCHPORCSPXIHLZ-UHFFFAOYSA-N |
Product Description
Applications: Diphenhydramine Hydrochloride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Diphenhydramine Hydrochloride (CAS 147-24-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Diphenhydramine Hydrochloride (CAS 147-24-0) has the molecular formula C17H22ClNO and a molecular weight of 291.14 g/mol. Reported properties include a solubility: greater than or equal to 100 mg/mL at 70.7 °F (NTP, 1992). It is also known as DIPHENHYDRAMINE HYDROCHLORIDE and Diphenhydramine HCl.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Diphenhydramine Hydrochloride
Property Insights of Diphenhydramine Hydrochloride
The XLogP value of 3.78 indicates that Diphenhydramine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.5 Ų, Diphenhydramine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Diphenhydramine Hydrochloride has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Diphenhydramine Hydrochloride?
The CAS number of Diphenhydramine Hydrochloride is 147-24-0.
What is the molecular formula of Diphenhydramine Hydrochloride?
The molecular formula of Diphenhydramine Hydrochloride is C17H22ClNO.
What is the molecular weight of Diphenhydramine Hydrochloride?
The molecular weight of Diphenhydramine Hydrochloride is 291.13898 g/mol.
What are the applications of Diphenhydramine Hydrochloride?
Diphenhydramine Hydrochloride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Diphenhydramine...
Where can I buy Diphenhydramine Hydrochloride?
You can request a quote for Diphenhydramine Hydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Diphenhydramine Hydrochloride?
Yes, CoreyChem provides custom synthesis services for Diphenhydramine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.